ea0056p678 | Paediatric endocrinology | ECE2018
Ntali Georgia
, Roidi Stella
, Michala Stavroula
, Paisiou Anna
, Peristeri Ioulia
, Michalakos Stephanos
, Vlachopapadopoulou Elpida
, Kitra Vassiliki
Introduction: Allogeneic bone marrow transplantation (BMT) represents the only effective approach to the cure of thalassemia major, offering high rates of success especially in a pediatric setting. Endocrine complications are expected in these patients due to both primary disease and BMT process. Iron overload, desferrioxamine treatment, cytotoxic agents used in the preparative regimen, and posttransplant immunosuppression period contribute to various endocrine disorders.<...